Neostigmine Methylsulfate CAS 51-60-5

Neostigmine Methylsulfate CAS 51-60-5 is a water-soluble quaternary ammonium API manufactured under strict enterprise internal control standards. It reversibly inhibits acetylcholinesterase, amplifying acetylcholine activity at neuromuscular junctions to strengthen skeletal muscle contraction and boost gastrointestinal peristalsis. We provide Bulk API Order service and maintain In Stock year-round, supporting mass production of injectable formulations and small trial batches for new drug development. Our product adopts multi-stage recrystallization purification, with all related impurities far below internal control limits, meeting strict quality requirements for sterile injection-grade raw materials.

Product Parameters (Specification)

Product Features and Applications

Product Features

Excellent water solubility: Highly soluble in water, ideal for preparing sterile injections without complex co-solvents, simplifying injection production processes;

Ultra-low impurity profile: Three key process impurities are nearly undetected, total impurities only 0.085%, lowering injection safety risks and simplifying impurity research for drug registration;

Stable physicochemical properties: Low moisture and ignition residue, resistant to oxidation, ensuring long-term storage stability without discoloration or degradation;

Targeted pharmacological selectivity: Strong excitatory effect on skeletal muscle, weak influence on central nervous system, with fewer central adverse reactions compared with similar cholinesterase inhibitors.

Application Scenarios

Anesthesia reversal injection raw material: Core API for formulations to eliminate residual muscle relaxation after general surgery, restoring spontaneous breathing and muscle tension in patientsDailyMed;

Myasthenia gravis treatment injections: Used for subcutaneous/intramuscular injection preparations to relieve persistent muscle weakness and fatigue in autoimmune myasthenia patients国家药品监...;

Postoperative intestinal & urinary recovery drugs: Raw material for injections treating paralytic ileus, postoperative abdominal distension and urinary retention by stimulating gastrointestinal smooth muscle peristalsisHPRA ...;

Veterinary anesthesia recovery products: Applied in animal surgical anesthesia adjuvant injections to reverse non-depolarizing muscle relaxants in livestock and companion animals;

Emergency antidote auxiliary raw material: Used in compound preparations for nerve toxin poisoning to relieve neuromuscular paralysis symptoms.

Procurement and Service Support

As your reliable Neostigmine Methylsulfate CAS 51-60-5 API Manufacturer, we deliver full-process professional procurement matching services:

Flexible tiered pricing for Bulk API Order: Long-term cooperative injection pharmaceutical enterprises enjoy volume discounts and priority production scheduling to shorten delivery cycles;

Stable In Stock inventory reserve: Multiple batches kept in constant storage, supporting urgent shipment to avoid production line shutdown caused by raw material shortage;

Complete regulatory supporting documents: Supply full internal standard compliant COA, batch manufacturing records, heavy metal test reports and MSDS to satisfy factory audit and drug registration demands;

Customized technical service: Professional injection formulation team provides guidance on sterile compounding, pH adjustment and stability optimization for downstream customers.