Methyl 4-hydroxy-2-methyl-1 CAS 35511-15-0

Methyl 4-hydroxy-2-methyl-1 CAS 35511-15-0 is a high-purity fine chemical intermediate manufactured strictly under internal enterprise standard TS-10-ZJ-052-01. It features a complete benzothiazine dioxide parent ring structure, serving as the key starting material for synthesizing oxicam-class nonsteroidal anti-inflammatory APIs. We support Mass Bulk Order and maintain Spot Stock year-round, fully meeting long-term continuous production demands of pharmaceutical manufacturers and medium-batch pilot scale-up. Our product adopts multi-stage recrystallization purification, with moisture and related substances far below standard limits, lowering side reaction rates in downstream amidation synthesis.

Product Parameters (Specification)

Product Features and Applications

Product Features

Large-scale stable production capacity: Mature industrial synthesis route, monthly ton-level output, fully supporting long-term mass production of NSAID raw material factories;

Low impurity profile: Ultra-low moisture and single/total impurities, effectively reducing impurity research workload for finished drug registration in USP/EP markets;

High synthesis reactivity: Ester group and phenolic hydroxyl group facilitate smooth amidation cyclization, improving the yield of piroxicam and meloxicam final APIs;

Good storage stability: No discoloration or degradation within shelf life, compatible with most conventional organic solvents for multi-step synthesis.

Application Scenarios

Core intermediate for oxicam anti-inflammatory APIs: Main raw material for piroxicam and meloxicam synthesis, used to produce oral tablets, capsules and external anti-inflammatory gels for arthritis pain relief;

Pharmaceutical impurity reference raw material: Can be processed into piroxicam EP impurity J standard substance for laboratory HPLC detection and analytical method verification;

Fine chemical custom synthesis: Used in R&D of novel COX-2 selective anti-inflammatory candidate drugs with benzothiazine skeleton;

Veterinary drug raw material intermediate: Applied in the production of animal anti-inflammatory and analgesic preparations for livestock joint inflammation and soft tissue injury.

Procurement and Service Support

As your reliable Dioxide Methyl Ester Manufacturer, we provide full industrial-grade intermediate supply solutions:

Competitive pricing for Mass Bulk Order: Tiered volume discounts for long-term cooperative manufacturers, priority production scheduling to shorten delivery cycles;

Persistent Spot Stock reserve: Multiple finished batches stored all year round, fast shipment to avoid production line shutdown caused by raw material shortage;

Complete regulatory supporting documents: Provide full TS-10-ZJ-052-01 compliant COA, batch manufacturing records, MSDS and transport qualification files for factory audit and drug registration;

Professional technical after-sales service: R&D team offers guidance on amidation process, recrystallization optimization and impurity control to boost downstream API yield.